SYNENTEC_NYONE_SCC AI

NYONE

Compact Image Cytometry

This fully automated cell imager and image analysis device is characterized by its mechanical robustness, small footprint, optical quality and functionality balanced features in a way that you will soon recognize that NYONE® is a valuable member of your team - ideal partner for medium-throughput laboratories with limited bench space!

Discover all the advantages

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Performs...

  • automated, fast and non-invasive brightfield and fluorescence imaging 
  • complete scan of a 96-well microplate in about 5 minutes
  • about 100 plates per 10 hours
  • integrated multi-parameter image analysis
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Supports...

  • SBS standard plate formats (384, 96, 24, 12, 6), dishes, T 25 flasks and microscope slides
  • customizable data and image export function for report creation, documentation and regulatory approval
  • transferability, as NYONE runs on the same software platform and supports the same applications as CELLAVISTA
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Offers...

  • small footprint to saves valuable labspace
  • up to 3 different magnifications
  • white light and 4 fluorescence excitation sources with up to 5 fluorescence emission filters

COMPARE TECHNICAL SPECIFICATIONS

 

NYONE® 4K HighEnd1

NYONE® Scientific

Throughput

100² plates / day

150² plates / day

Objective capacity

3

3

Selectable Resolutions1

1.3 µm @ 4x
0.9 µm @ 10x
0.53 µm @ 20x

6.5 µm @ 2x optional
3.25 µm @ 4x
1.3 µm @ 10x
0.65 µm @ 20x
0.33 µm @ 40x optional

Automated whole well/whole plate imaging

✓

✓

Sample types

SBS plate format (1536, 384, 96 wells and less), culture dishes and microscope slides

SBS plate format (1536, 384, 96 wells and less), culture dishes and microscope slides

Camera

8 bit progressive scan
CMOS

16 bit sCMOS

Pixel density

4496 x 4496
20.2 MPx

2048 x 2048
4.19 MPx

Quantum efficiency
(relevant to detect weak fluorescence)

~66 %

~80 %

Light source

High performance long-life LED

High performance long-life LED

Illumination / Fluorescence1

Brightfield and 4 fluorescence excitation sources, up to 5 fluorescence emission filters

Brightfield and 4 fluorescence excitation sources, up to 5 fluorescence emission filters

Temp.-control

×

×

Image acquisition- & device controlling software4

YT-SOFTWARE®4

YT-SOFTWARE®4

Automation-ready set up

✓

×

Software-interface for automation

✓

✓

Batch processing interface

✓

✓

External barcode-reader

Optional

Optional

1 Different system configurations like e.g. basic systems with brightfield only or customized filter and objective lenses set-ups are available.
2 Throughput per day depends on experiment configurations (e.g. exposure time, plate type, focus options, # of imaging channels…).
3 CELLAVISTA® can be equipped with the ibidi® heating and incubation system (other systems not tested). Due to pH-shift and consequent cell stress a heating option only is not recommended.
4 YT-SOFTWARE® includes the same image analysis tools for both CELLAVISTA® and NYONE®. Differences in usable applications arise only due to different hardware configurations (e.g. different illuminations or camera chips).
5 Hardware automation-package available.

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Different Variants of NYONE®

SCIENTIFIC Line

SCIENTIFIC Product Line

Equipped with 16-bit sCMOS cameras and high-NA objectives, the SCIENTIFIC series delivers superior resolution and a wide dynamic range. With over 80% quantum efficiency, it excels at detecting weak fluorescence, boosting signal-to-noise for clearer, more reliable results.

Discover SCIENTIFIC product line
4K Line Single cell cloning

4K Product Line

True 0.8 µm resolution at 10x. Native 4K clarity without sacrificing throughput. Perfect for detecting monoclonality in SCC and even the smallest cell fragments in brightfield.

Designed for speed, precision, and flexibility.

Discover 4K product line

Advanced Technological Features

  • Agitation-free imaging of adherent and suspension cells through harmonic motion
  • Reliably reproducible measurements through high-precision scan stage control
  • Ultra-fast filter wheel – 40 ms position changing time (e.g. well suited for FRET assays)
  • Excellent well edge illumination of microplates
  • Perfect, seemless image stitching
  • Ultra-fast electronically switched excitation sources - less than 5 ms switching time
  • Always in focus due to specially designed laser autofocus mechanisms
  • Leverages the flexibility of automated image analysis to maximize the output of your cellular assays

 

To get an overview compare all high throughput microscopes  >>>