Automated high throughput cell imaging

Automated high throughput imaging cell microscop.

CELLAVISTA 4

CELLAVISTA® 4 is a fully automated cell imager designed for the characterization of cells as an integral step of your research, development and production process. The CELLAVISTA® 4 imaging system support state-of-the-art automation and can be easily linked with Plate Stackers, Cell printers, Incubators, Liquid Handlers & Clone Pickers.

 Automated high throughput imaging cell microscop.

NYONE

Due to the fact that many labs run their application in medium throughput, NYONE® is the perfect choice to save money and bench space. This fully automated cell imager is characterized by its mechanical robustness, optical quality and functionality balanced features in a way that you will soon recognize that NYONE® is a reliable member of your team.

RESOLUTION MATTERS

COMPARE TECHNICAL SPECIFICATIONS

 

CELLAVISTA® 4K HighEnd1

NYONE® 4K HighEnd1

CELLAVISTA® 4 Scientific

NYONE® Scientific

Throughput

250² plates / day

100² plates / day

250² plates / day

150² plates / day

Objective capacity

4

3

4

3

Selectable Resolutions1

3.3 µm @ 2x optional
1.3 µm @ 4x
0.9 µm @ 10x
0.53 µm @ 20x
0.35 µm @ 40x

1.3 µm @ 4x
0.9 µm @ 10x
0.53 µm @ 20x

6.5 µm @ 2x optional
3.25 µm @ 4x
1.3 µm @ 10x
0.65 µm @ 20x
0.33 µm @ 40x

6.5 µm @ 2x optional
3.25 µm @ 4x
1.3 µm @ 10x
0.65 µm @ 20x
0.33 µm @ 40x optional

Automated whole well/whole plate imaging

Sample types

SBS plate format (6-384 wells), culture dishes and microscope slides

SBS plate format (6-384 wells), culture dishes and microscope slides

SBS plate format (6-384 wells), culture dishes and microscope slides

SBS plate format (6-384 wells), culture dishes and microscope slides

Camera

8 bit progressive scan
CMOS

8 bit progressive scan
CMOS

16 bit sCMOS

16 bit sCMOS

Pixel density

5440x 5440
29.6 MPx

4496 x 4496
20.2 MPx

2048 x 2048
4.19 MPx

2048 x 2048
4.19 MPx

Quantum efficiency
(relevant to detect weak fluorescence)

~57 %

~66 %

> 80 %

~80 %

Light source

High performance long-life LED

High performance long-life LED

High performance long-life LED

High performance long-life LED

Illumination / Fluorescence1

Brightfield and 6 fluorescence excitation/emission channels

Brightfield and 4 fluorescence excitation sources, up to 5 fluorescence emission filters

Brightfield and 6 fluorescence excitation/emission channels

Brightfield and 4 fluorescence excitation sources, up to 5 fluorescence emission filters

Temp.-control

Possible3

×

Possible3

×

Image acquisition- & device controlling software4

YT-SOFTWARE®4

YT-SOFTWARE®4

YT-SOFTWARE®4

YT-SOFTWARE®4

Automation-ready set up

×

Software-interface for automation

Batch processing interface

External barcode-reader

Optional

Optional

Optional

Optional

1 Different system configurations like e.g. basic systems with brightfield only or customized filter and objective lenses set-ups are available.
2 Throughput per day depends on experiment configurations (e.g. exposure time, plate type, focus options, # of imaging channels…).
3 CELLAVISTA® can be equipped with the ibidi® heating and incubation system (other systems not tested). Due to pH-shift and consequent cell stress a heating option only is not recommended.
4 YT-SOFTWARE® includes the same image analysis tools for both CELLAVISTA® and NYONE®. Differences in usable applications arise only due to different hardware configurations (e.g. different illuminations or camera chips).
5 Hardware automation-package available.