NYONE
Compact Image Cytometry
This fully automated cell imager and image analysis device is characterized by its mechanical robustness, small footprint, optical quality and functionality balanced features in a way that you will soon recognize that NYONE® is a valuable member of your team - ideal partner for medium-throughput laboratories with limited bench space!
Discover all the advantages
COMPARE TECHNICAL SPECIFICATIONS
|
NYONE® 4K HighEnd1 |
NYONE® Scientific |
|
|---|---|---|
|
Throughput |
100² plates / day |
150² plates / day |
|
Objective capacity |
3 |
3 |
|
Selectable Resolutions1 |
1.3 µm @ 4x |
6.5 µm @ 2x optional |
|
Automated whole well/whole plate imaging |
✓ |
✓ |
|
Sample types |
SBS plate format (6-384 wells), culture dishes and microscope slides |
SBS plate format (6-384 wells), culture dishes and microscope slides |
|
Camera |
8 bit progressive scan |
16 bit sCMOS |
|
Pixel density |
4496 x 4496 |
2048 x 2048 |
|
Quantum efficiency |
~66 % |
~80 % |
|
Light source |
High performance long-life LED |
High performance long-life LED |
|
Illumination / Fluorescence1 |
Brightfield and 4 fluorescence excitation sources, up to 5 fluorescence emission filters |
Brightfield and 4 fluorescence excitation sources, up to 5 fluorescence emission filters |
|
Temp.-control |
× |
× |
|
Image acquisition- & device controlling software4 |
YT-SOFTWARE®4 |
YT-SOFTWARE®4 |
|
Automation-ready set up |
✓ |
× |
|
Software-interface for automation |
✓ |
✓ |
|
Batch processing interface |
✓ |
✓ |
|
External barcode-reader |
Optional |
Optional |
1 Different system configurations like e.g. basic systems with brightfield only or customized filter and objective lenses set-ups are available.
2 Throughput per day depends on experiment configurations (e.g. exposure time, plate type, focus options, # of imaging channels…).
3 CELLAVISTA® can be equipped with the ibidi® heating and incubation system (other systems not tested). Due to pH-shift and consequent cell stress a heating option only is not recommended.
4 YT-SOFTWARE® includes the same image analysis tools for both CELLAVISTA® and NYONE®. Differences in usable applications arise only due to different hardware configurations (e.g. different illuminations or camera chips).
5 Hardware automation-package available.
Different Variants of NYONE®
SCIENTIFIC Product Line
Featuring high-sensitivity 16-bit sCMOS cameras combined with high numerical aperture objectives, the SCIENTIFIC instrument series achieve better resolution in a higher dynamic range and employ a quantum efficiency of more than 80% (relevant to detect weak fluorescence). This enables the performance of higher dynamic range assays due to a better signal-to-noise (S/N or SNR) ratio.
4K Product Line
Native 4K imaging does not compromise throughput, it simply increases resolution and clarity. This gives you the possibility especially in brightfield area to check for monoclonality of your SCC applications and not miss a single cell fragment.
Advanced Technological Features
- Agitation-free imaging of adherent and suspension cells through harmonic motion
- Reliably reproducible measurements through high-precision scan stage control
- Ultra-fast filter wheel – 40 ms position changing time (e.g. well suited for FRET assays)
- Excellent well edge illumination of microplates
- Perfect, seemless image stitching
- Ultra-fast electronically switched excitation sources - less than 5 ms switching time
- Always in focus due to specially designed laser autofocus mechanisms
- Leverages the flexibility of automated image analysis to maximize the output of your cellular assays
To get an overview compare all high throughput microscopes >>>
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