SYNENTEC and myriameds myrIMage für myrPlates imaging. Video optical high-throughput analysis für IND ICH hERG drug testing.

myrImager

Drug-screening on contractile tissue

The myrImager is a video-optical high-throughput imaging platform designed to work seamlessly with the myriamed 48-well 3D cell/tissue culture plates. Together, they provide an advanced imaging solution for iPSC-derived tissue models used in research and drug screening aligned with ICH hERG testing guidelines.

 

Powered by the innovative poleDance software, the myrImager enables independent data evaluation with flexible scheduling, customizable plate layouts, and precise measurement of pole movement kinetics.

 

Discover all the advantages

icon-performs.svg

Performs...

  • one shot whole plate imaging
  • video-optical drug screening for long term and acute measurements
  • imaging of 48 samples (tissues) in 60s
  • contraction kinetics (force-time curves) for funtional IC50/EC50 studies
icon-supports.svg

Supports...

  • 48-well 3D cell/tissue culture myrPlates
  • functional analysis of contractile tissue such as cardiomyocytes, skeletal muscle or connective tissue
  • spontaneously contracting tissue or contraction by stimulation of optogenetic receptor
icon-offers.svg

Offers...

  • small footprint
  • easy integration into standard incubator for 24/7 long-term chronic measurements for rare events (e.g. arythmia) with ease-of-use external control to prevent contamination
  • robust architecture for reliable, highly reproducible measurements

Best-in-class tissue imager for functional kinetics

The myrImager was developed based on myriamed’s unrivaled expertise in pluripotent stem cell-based tissue formulations and their phenotypic analyses. It images heart muscle, skeletal muscle and connective tissue formulations prepared in myriamed proprietary myrPlates and performs  contraction kinetics (force-time curves) e.g. for funtional IC50/EC50 studies.

 

SYNENTEC as expert in microscopic solutions for automated high-content screens took on the challenge to re-engineer the myrImager to develop it into a unique product for the stem cell & drug-screening community.

 

The myrImager operates independently from SYNENTEC’s YT Image Analysis Software on a novel data evaluation platform. Powered by the innovative poleDance software, it offers advanced capabilities such as measuring pole movement kinetics with flexible scheduling options and customizable plate layout configurations.