The development of new biopharmaceuticals plays an important role in the treatment of serious diseases such as cancer, autoimmune- and inflammatory diseases. Producing such a biopharmaceutical, like monoclonal antibodies (mAbs), requires many optimization steps between the start cell and the final production process.
Like most proteins, mAbs tend to form aggregates during manufacturing, negatively impacting the quality, safety and efficacy of these biotherapeutics. It is very expensive to remove those aggregates during the purification steps. Therefore, one goal is to optimize the process in such a way that it does not even come to the formation of these mAb-aggregates.
Using the mAbregation-Kit® in combination with SYNENTEC's imaging systems provides an ideal way to optimize the efficiency of your process, giving the highest yield of the desired biopharmaceutical. The containing fluorescence-dye specifically stained mAb-aggregates, which can be analyzable with the mAB-Aggregation Screening Operator of SYNENTEC's YT-software®.
Ordering Information for mAbregation-Kit®
- 2 x 4 mL mAbregation® ready-to-use staining solution
- Precipitation reagent
- Cat# 200115
- 129,- € (+ taxes & shipping costs)
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